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Prototype dental vaccine could neutralise harmful bacteria in the mouth


The world’s first dental vaccine could limit, or even replace, the need for gum surgery according to scientists from Melbourne, Australia. The breakthrough vaccination could work by stimulating the body’s own defenses to fight infection and reduce or eliminate harmful bacteria.

The team of Australian scientists have been working on the vaccine for almost fifteen years, alongside the biotech company CSL, who specialise in research, development and manufacture of medicines and vaccines to prevent serious conditions. The aim of this oral hygiene research and development was to produce a preventative medicine that could tackle periodontitis and general gum disease.

An article appeared in the NPJ Vaccines Journal earlier this week, which showed the findings of the prototype. The results suggested that it was extremely effective in triggering the natural human immune response to the bacteria Porphyromonas Gingivalis, and showed a neutralisation of this common culprit of bone and tissue loss. Scientists are hoping that a fully-fledged version of the vaccine could be available to the public within, as little as, a few years’ time. Not only would this be good news for overall health, considering it is linked to heart disease, dementia, and some cancers, but it would also mean that people would potentially need less invasive treatment from their dentist.




Diet ‘impacts dental health’


Different foods have been foound to effect teeth differently.

While it is well known that eating sugary foods is detrimental to oral health and could result in a trip to the emergency dentist, a study has been carried out showing which foods can be the most damaging. dental health

Dental Plans reported research published in the journal Pediatric Dentistry revealed the breakfast food which promoted the worst amounts of acid creation – leading to dental plaque – were those which contained raisins and bran.

Dr Christine Wu, director of cardiology research at the University of Illinois at Chicago, noted this food type showed significant acid production into the “well-documented danger zone”.

Elsewhere, a vaccine that could help stop gum disease has been created by pharmaceutical company CSL.

The project has now entered a phase where it will be tested on mice, with human trials likely to begin in the near future if it shows positive results.

Gum disease vaccine in development


A new vaccine to tackle gum disease is in development.

A new vaccine to help tackle gum disease is being developed in Australia. gum disease vaccine

Pharmaceutical company CSL has been working with researchers from universities across the country to help create a vaccine that could help reverse the effects of gum disease, as well as stopping its development in the first place.

“Periodontitis is a serious disease and dentists face a major challenge treating it, because most people will not know they have the disease until it’s too late,” Professor Eric Reynolds of the University of Melbourne commented.

Dr Andrew Cuthbertson, CSL’s chief scientific officer, noted work on this new inoculation has been underway for the last ten years and has now reached the phase where it will be tested on mice, with human trials the next step.

Elsewhere, research carried out at the New York University recently revealed a link between gum disease and diabetes.

The study found 90 per cent of patients who have gum disease are at high risk of developing the illness.

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